[POE2 0.5.5] (Nerfed) Everything About Azmeri Spirit Strongbox Farm Strategy.

Strategy

Azmeri Spirit Strongbox farming chains spirits through strongboxes until every box on the map is carrying a large stack of spirits, then opens them all at once. The chain only starts when a Sacred Spirit (orange wisp) appears. With the Sacred Sap keystone choice, any monster possessed by a sacred spirit is also possessed by another random spirit, so every strongbox you open releases monsters that carry more spirits forward. The Hare variant revives possessed monsters (each revive adds spirits), while the Fox variant upgrades monster rarity, and with Hilda’s mastery possessed uniques release spirits on death.

Monsters spawned from a possessed strongbox inherit its spirits, so you feed the sacred spirit into the first box and let it hop from box to box. In good maps the creator reports around 200 Divine Orbs on average, plus frequent Rite of Passage drops and real chances at chase uniques. Note that the video title flags this strategy as nerfed, so expect lower returns than the showcase.

This is a high-effort, high-investment method aimed at strong characters with good PCs. Prep costs about 10 divines per map, roughly half of maps get abandoned for having no sacred spirit, and late-chain fights can be extremely laggy.

Atlas Tree & Setup

Tablets: three Expedition tablets with “Expeditions contain 2 buried strongboxes” plus an increased Azmeri spirit chance mod, and one Overseer tablet with “+2 additional Azmeri spirits”. Four Overseer tablets is an older, weaker option.
Maps: T15 eight-mod maps with maximum monster rarity (around 103%), because only rare and unique monsters can be possessed.
Biome: an Ezomyte City region, which counts as both city (about 54% stronger tablet effect, which turns 2 strongboxes into 3) and grass (more sacred spirits). Two Expeditions with about nine strongboxes each gives roughly 18 boxes per map.
Map modifier: 200% Delirium is preferred over Sacred Bloom Wildwood for extra loot and Distilled Emotions.
Atlas master: Hilda for strong builds (Fox-only maps are still worth running); Doryani for an extra portal and juicier Hare maps, but you will skip Fox-only maps.
Atlas nodes: grass biome, the Sacred Sap spirit node, Azmeri spirits over extra strongboxes, and one extra explosive charge. Exact picks are shown in the source video.

Investment & Returns

Investment: high (about 10 div per map in tablets and maps, plus strongbox crafting currency)
Returns: high but swingy; the creator estimates roughly 50–200+ div in maps where the chain works
Scales with volume: you abandon about 50% of maps, so profit comes from running many

Step-by-step

Use a strict loot filter (skip low-value currency) to reduce lag. Do not hold Alt.
Bring Cryptic Keys, Omen of the Hunt and crafting currency (Chaos, Alchemy, Regal, Exalted, Augment, Transmute).
Fully clear the map, including the boss, without touching any orange sacred spirit.
If no sacred spirit appeared, leave the map (or a Fox-only map if you run Doryani).
Activate the sacred spirit once only strongboxes remain, so it can only possess a box.
Roll the first box carefully until it has “guarded by two rare packs” or “7–8 monster packs”, then open it with Omen of the Hunt and a Cryptic Key.
Kill everything, let released spirits move to the next box, and repeat until every box holds many spirits.
Explode the corpses to reduce lag, then place explosives over as many strongboxes as possible and detonate.

Risks

The title marks the method as nerfed, so showcase numbers may not hold
Heavy lag can crash the game or make re-logging hard
Builds that destroy corpses (freeze/shatter, some cold builds, Headhunter) break the Hare revive chain
One death can wipe a whole map’s progress unless you run Doryani’s extra portal

Credits & Source

Method credited to KingPinUwU. See the source video: [POE2 0.5.5] (Nerfed) Everything About Azmeri Spirit Strongbox Farm Strategy.